After examining 8 separate studies, the researchers concluded that men who took tramadol—an opioid pain reliever prescribed off-label—were able to extend their sack sessions longer than guys who popped a placebo.
The drug was also just as effective at delaying premature ejaculation (PE) as paroxetine, an antidepressant commonly used to treat the condition. And it performed even better than behavioral therapy or other common PE meds, like sildenafil (Viagra) or the numbing lidocaine gel.
More research is needed to fully understand how a narcotic pain reliever can keep your boner alive longer. But researchers speculate that the drug affects receptors in the brain that alter neurotransmitters and delay the ejaculation reflex, says review author Catherine Hood, BA, BM BCh (Oxon).
And while these results are promising, they should be interpreted with caution. That’s because many of these trials didn’t properly report important steps of their study, such as whether or not their form of treatment was concealed, says lead reviewer Marrissa Martyn-St James, Ph.D., M.Sc.
Plus, there are still questions about the dosage, duration, and side effects of tramadol, since no long-term studies on the efficacy and safety of it for PE have been conducted, says Dr. Hood.
“At the moment, there is no perfect treatment for premature ejaculation,” she says. “Every man is different and will respond to different treatment options.”
What is Premature Ejaculation ?
Premature ejaculation occurs when a man ejaculates sooner during sexual intercourse than he or his partner would like. Premature ejaculation is a common sexual complaint. Estimates vary, but as many as 1 out of 3 men say they experience this problem at some time.
As long as it happens infrequently, it's not cause for concern. However, you might be diagnosed with premature ejaculation if you:
1) Always or nearly always ejaculate within one minute of penetration
Are unable to delay ejaculation during intercourse all or nearly all of the time
2) Feel distressed and frustrated, and tend to avoid sexual intimacy as a result
Both psychological and biological factors can play a role in premature ejaculation. Although many men feel embarrassed talking about it, premature ejaculation is a common and treatable condition. Medications, counseling and sexual techniques that delay ejaculation — or a combination of these — can help improve sex for you and your partner.
What Should You Do If You Have It?
Because it’s such a common condition, don’t think of it as a death sentence for your sex life. Instead, focus on finding a solution.
Dr. Hood recommends having a physical exam and full discussion with your urologist to determine what might be causing your PE. You could just be psyching yourself out—or your penis may be pointing to a more serious biological problem.
If you do want to try tramadol for your PE, make sure you have an honest discussion with your doc about your own medical history—and the drug’s potential side effects, like nausea, headache and dizziness—to determine whether it might be a suitable treatment option for you.
One important note: If your doc does start you on tramadol, just be aware that it will be prescribed off-label, meaning to treat a condition for which drug is not officially approved.
This practice is legal and is commonly used by many doctors. But it often lacks the degree of scientific scrutiny that comes along with FDA approval for certain uses—which makes doctor-patient communication even more important.
Those not to take Tramadol
You should not take tramadol if you have severe breathing problems, a blockage in your stomach or intestines, or if you have recently used alcohol, sedatives, tranquilizers, narcotic medication, or an MAO inhibitor (isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others).
Tramadol can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially person using the medicine without a prescription.
Fatal side effects can occur if you use tramadol with alcohol, or with other drugs that cause drowsiness or slow your breathing.
Seizures (convulsions) have occurred in some people taking this medicine. Tramadol may be more likely to cause a seizure if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, narcotic, or medicine for nausea and vomiting
Tramadol can interact with many other drugs and cause dangerous side effects or death. Tell your doctor about all your current medicines and any you start or stop using.
Do not crush the tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.
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Source: menshealth, mayoclinic and drugs.com
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